Abstract: A very important step in radiotherapy during the treatment process is the procedure of image processing (Matlab) and the radiation doses calculations. Many commercial software and techniques are developed for these procedures. The methodology of using numerical methods in medical imaging and radiotherapy for training and simulations is very important for students and researches in laboratories before clinical practice. Using Matlab, we can analyze data, develop algorithms, and create models and applications. The language, tools, is built in math functions enable us to explore multiple approaches and reach a solution faster than with spreadsheets or traditional programming languages, such as C/C++ or Java. Matlab is a high-level language and interactive environment for numerical computation, visualization, and programming. From 2010 our team is working to adapt a module in Matlab environment for Medical Physics and Medical Imaging Technicians based on several modules in Matlab. First, we describe the computational environment for radiotherapy research, developed to facilitate reproducible research in radiation oncology treatment planning in Matlab environment, as a basic framework to make interinstitutional treatment planning research more feasible. At the end we describe the first Albanian module for training and simulation in radiotherapy called PPIR1 . One of the most important applications of this module is medical images processing, visualization and structure contouring for radiotherapy treatment. The simulation procedure of linear accelerator and the configuration of beams for tumor treatments is another application of this module. The dose calculation on this module is based on Eudmodel for dose volume histograms (DVH), which in radiotherapy treatment plan evaluation relies on an implicit estimation of the tumor normal tissue complication probability and control probability
